The following are the most frequently asked questions about Align products and
probiotics for healthcare professionals.
General Information
A. Align is a daily probiotic supplement that helps support gastrointestinal health. Align Digestive Support (Bifidobacterium 35624™) helps relieve and manage IBS symptoms. For more information about IBS, see our mini video series available on our product information page.
A. Align supplements the digestive system with good bacteria to help promote and support a healthy digestive system and maintain digestive health.
Additionally, Align Women’s Dual Probiotic combines the health benefits of Align with two women’s probiotics and botanical chaste tree to support vaginal health, help replenish healthy bacteria, and help relieve premenstrual symptoms and help relieve symptoms associated with menopause.
Q: Is Align a laxative?
A: No, Align is a daily probiotic supplement that naturally helps promote and support a healthy digestive system*.
Q: Who should take Align?
A: Align can be taken by patients looking for an effective probiotic supplement for the relief and management of IBS symptoms, including abdominal discomfort, gas, and bloating. With continued daily use, Align helps to fortify a patient’s digestive system with healthy bacteria to provide support for patients with IBS.
Align Women’s Dual action is for women seeking a probiotic supplement for the relief and management of IBS symptoms. With additional probiotics to help restore and maintain a healthy vaginal flora and herbal medicine, Chaste Tree, to help relieve premenstrual symptoms and symptoms associated with menopause, such as hot flashes.
A. Bifidobacterium 35624™ is the trademarked strain of beneficial bacteria, Bifidobacterium longum longum 35624™ (or Bifidobacterium 35624). Bifidobacterium 35624™ is the probiotic strain found only in Align Digestive Support capsules and chewable tablets. The specific and pure strain of Bifidobacterium 35624™ found in Align relieves and manages symptoms of IBS such as gas, bloating, and abdominal discomfort. To see why strain specificity is importantt click here
Q: Does Align offer free patient samples?
A: Currently, Align does not offer free patient samples. However, we do have patient brochures with coupons available to order through the Physicians Pharmalink program. To stay up to date about future sample programs, please subscribe to our newsletter.
Q: What are the benefits of Align Women’s Dual Action capsules?
A: Align Women’s Dual Action combines the probiotic Bifidobacterium 35624™ developed by gastroenterologists, with feminine health probiotics LA-14® & HN001™ to help restore and maintain healthy vaginal flora. Made with Chaste tree botanical, this supplement also helps to relieve premenstrual symptoms and symptoms associated with menopause.
Taking Align
A. Align can be taken at any time of day, with or without food. We recommend that patients take it as part of their daily routine, at a time that will be easy to remember.
A. Consider if your patient’s health conditions and medications are appropriate for use with Align probiotic strains and the other botanical ingredients in the specific product before recommending Align Probiotics. Probiotics are not recommended for patient with immune suppressed conditions.
Do not use if you are pregnant, breastfeeding, or attempting to conceive
A: Align probiotics with our Bifidobacterium 35624™ strain comes in capsules and great-tasting chewable tablets. Align also has probiotic gummies and but these contain a different probiotic strain and thus offer different benefits.
Additionally, Align Women’s Dual Health probiotics combine the Bifidobacterium 35624™ strain with two additional women’s health probiotics and botanical chaste tree to support vaginal health, help replenish healthy bacteria, and help relieve premenstrual symptoms and help relieve symptoms associated with menopause.
A. Align Digestive Support Chewables contain the same effective probiotic strain as Align Digestive Support Capsules but in a great-tasting Strawberry & Banana Smoothie flavoured chewable tablet.
A: It is recommended that patients take their Align digestive support once Daily.
A. The time-to-effect and specific effect of probiotics differs from person to person. because we each have a unique gut flora and health situation. It takes time for our microbiome and our body to adjust to a new probiotic. The specific probiotic strain in Align Digestive Support should be taken once daily on a consistent basis to for best results. We recommend patients use Align Digestive support once daily for at least a month to give their body time to adjust to probiotic strain and see the benefits it can offer them.
A: Align has no known interactions with medications. However, some antibiotics may make Align less effective. For example, Bifidobacterium 35624, the probiotic in Align, is susceptible to antibiotics with gram-positive coverage, including ampicillin, ciprofloxacin, erythromycin, gentamycin, penicillin, and vancomycin. Consider if your patient’s health conditions and medications are appropriate for use with Align probiotic strains and the other botanical ingredients in the specific product before recommending Align Probiotics.
Do not use if you are pregnant, breastfeeding, or attempting to conceive
Health & Safety
A. In clinical studies, there was no significant difference in side-effects between Align Digestive Support and placebo. Side effects, if present, tend to be mild. Some patients experience gas and/or bloating in the first few weeks. This may be temporary, while their digestive system adjusts to Align Digestive Support and Align Women’s Dual Action
A: Align Digestive Support Chewables can be used by children 12 and older once daily. Align Women’s Dual Action is recommended for adults only, do not use if you are pregnant, breastfeeding, or attempting to conceive
A: Consistent with clinical studies on Bifidobacterium 35624, each Align capsule contains at least 1 x 109 (one billion) (4 mg) live bacteria/CFU when manufactured and provides an effective level of bacteria (1x 107 CFU) until at least the “best by” date.
A. Align Women’s Dual Action provides six billion (6 x 109 CFU) of combined bacteria (HN001, La-14, and 35624).
A: Consistent with clinical studies on Bifidobacterium 35624, each Align Chewable tablet provides an effective level of bacteria (1x 107 CFU) until at least the “best by” date.
A. No. According to the International Scientific Association for Probiotics and Prebiotics (ISAPP), different probiotics have been shown to be effective at various levels. A product with a larger dose is not always better. The dose should match studies demonstrating their benefit(s), which typically ranges from 100 million – 10+ billion cfu/dose.1
A. Align does not need to be refrigerated. The Bifidobacterium 35624™ in Align has been freeze-dried and does not require refrigeration. Align has been formulated and tested to confirm that it remains effective without refrigeration for the 24-month shelf life. Patients can take it any time or anywhere that’s convenient.
A: To maximize the effectiveness of Align, Align should be stored in its original pack. Your patients should store the package at room temperature (24° C/75° F). We recommend that patients do not put Align into other packages, including pill keepers.
Ingredients
A: Yes, Align has been scientifically tested and is a gluten-free probiotic supplement.
A: Align is not created with ingredients that would be expected to contain soy, but it is not guaranteed that Align is 100% soy free.
A: No, Align does contain milk and sodium caseinate (milk protein). Therefore, patients who are lactose intolerant may not be able to tolerate Align.
A: Align is not created with ingredients that would be expected to contain lactose, but it is not guaranteed that Align is 100% lactose free.
Reference:
‡Among Doctors and Gastroenterologists who recommended a brand of probiotic in ProVoice surveys 2015 to 2023.